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Molecular Coupling of S4 to a K(+) Channel's Slow Inactivation Gate

The mechanism by which physiological signals regulate the conformation of molecular gates that open and close ion channels is poorly understood. Voltage clamp fluorometry was used to ask how the voltage-sensing S4 transmembrane domain is coupled to the slow inactivation gate in the pore domain of th...

詳細記述

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書誌詳細
主要な著者: Loots, Eli, Isacoff, Ehud Y.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229480/
https://ncbi.nlm.nih.gov/pubmed/11055991
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