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Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability
Members of the SLC4 bicarbonate transporter family are involved in solute transport and pH homeostasis. Here we report that disrupting the Slc4a10 gene, which encodes the Na(+)-coupled Cl(−)–HCO(3)(−) exchanger Slc4a10 (NCBE), drastically reduces brain ventricle volume and protects against fatal epi...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2008
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2224208/ https://ncbi.nlm.nih.gov/pubmed/18165320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705487105 |
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