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The fraction 1 and V protein antigens of Yersinia pestis activate dendritic cells to induce primary T cell responses

The F1 and V antigens of Yersinia pestis, despite acting as virulence factors secreted by the organism during infection, also combine to produce an effective recombinant vaccine against plague, currently in clinical trial. The protective mechanisms induced by rF1 + rV probably involve interactions w...

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Autores principales: Kingston, R, Burke, F, Robinson, J H, Bedford, P A, Jones, S M, Knight, S C, Williamson, E D
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219336/
https://ncbi.nlm.nih.gov/pubmed/17645768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03452.x
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