The fraction 1 and V protein antigens of Yersinia pestis activate dendritic cells to induce primary T cell responses

The F1 and V antigens of Yersinia pestis, despite acting as virulence factors secreted by the organism during infection, also combine to produce an effective recombinant vaccine against plague, currently in clinical trial. The protective mechanisms induced by rF1 + rV probably involve interactions w...

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Autors principals: Kingston, R, Burke, F, Robinson, J H, Bedford, P A, Jones, S M, Knight, S C, Williamson, E D
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2007
Matèries:
Translational Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219336/
https://ncbi.nlm.nih.gov/pubmed/17645768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03452.x
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