Gremlin-mediated Decrease in Bone Morphogenetic Protein Signaling Promotes Pulmonary Fibrosis

Rationale: Members of the transforming growth factor (TGF)-β superfamily, including TGF-βs and bone morphogenetic proteins (BMPs), are essential for the maintenance of tissue homeostasis and regeneration after injury. We have observed that the BMP antagonist, gremlin, is highly up-regulated in idiop...

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Библиографические подробности
Главные авторы: Myllärniemi, Marjukka, Lindholm, Pamela, Ryynänen, Merja J., Kliment, Corrine R., Salmenkivi, Kaisa, Keski-Oja, Jorma, Kinnula, Vuokko L., Oury, Tim D., Koli, Katri
Формат: Artigo
Язык:Inglês
Опубликовано: American Thoracic Society 2008
Предметы:
G. Interstitial Lung Disease
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2218851/
https://ncbi.nlm.nih.gov/pubmed/17975199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200706-945OC
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