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TRPM7 Provides an Ion Channel Mechanism for Cellular Entry of Trace Metal Ions

Trace metal ions such as Zn(2+), Fe(2+), Cu(2+), Mn(2+), and Co(2+) are required cofactors for many essential cellular enzymes, yet little is known about the mechanisms through which they enter into cells. We have shown previously that the widely expressed ion channel TRPM7 (LTRPC7, ChaK1, TRP-PLIK)...

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Autors principals: Monteilh-Zoller, Mahealani K., Hermosura, Meredith C., Nadler, Monica J.S., Scharenberg, Andrew M., Penner, Reinhold, Fleig, Andrea
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217320/
https://ncbi.nlm.nih.gov/pubmed/12508053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028740
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