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Comparison of lymphoblast mitochondria from normal subjects and patients with Barth syndrome using electron microscopic tomography

Barth syndrome (BTHS) is a mitochondrial disorder that is caused by mutations in the tafazzin gene, which affects phospholipid composition. To determine whether this defect leads to alterations in the internal three-dimensional organization of mitochondrial membranes, we applied electron microscopic...

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Autors principals: Acehan, Devrim, Xu, Yang, Stokes, David L., Schlame, Michael
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2215767/
https://ncbi.nlm.nih.gov/pubmed/17043667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.3700480
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