Elastase Release by Transmigrating Neutrophils Deactivates Endothelial-bound SDF-1α and Attenuates Subsequent T Lymphocyte Transendothelial Migration

Leukocyte trafficking to sites of inflammation follows a defined temporal pattern, and evidence suggests that initial neutrophil transendothelial migration modifies endothelial cell phenotype. We tested the hypothesis that preconditioning of human umbilical vein endothelial cells (HUVEC) by neutroph...

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Main Authors: Rao, Ravi M., Betz, Travis V., Lamont, Deanna J., Kim, Michael B., Shaw, Sunil K., Froio, Richard M., Baleux, Françoise, Arenzana-Seisdedos, Fernando, Alon, Ronen, Luscinskas, Francis W.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2004
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211969/
https://ncbi.nlm.nih.gov/pubmed/15381727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040499
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