A Defect in Nucleosome Remodeling Prevents IL-12(p35) Gene Transcription in Neonatal Dendritic Cells

To gain insight into the inability of newborns to mount efficient Th1 responses, we analyzed the molecular basis of defective IL-12(p35) expression in human neonatal monocyte-derived dendritic cells (DCs). Determination of IL-12(p35) pre-mRNA levels by real-time RT-PCR revealed that transcriptional...

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Bibliografiske detaljer
Main Authors: Goriely, Stanislas, Van Lint, Carine, Dadkhah, Réza, Libin, Myriam, De Wit, Dominique, Demonté, Dominique, Willems, Fabienne, Goldman, Michel
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2004
Fag:
Brief Definitive Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211877/
https://ncbi.nlm.nih.gov/pubmed/15051764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031272
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