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Inactivation of the UNC5C netrin-1 receptor is associated with tumor progression in colorectal malignancies
BACKGROUND & AIMS: The UNC5H netrin-1 receptors (UNC5H1-3, or UNC5A-C) belong to the functional dependence receptors family that share the ability to induce apoptosis in the absence of their ligands. Such a trait has been hypothesized to confer a tumor suppressor activity. Indeed, cells harborin...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2211510/ https://ncbi.nlm.nih.gov/pubmed/17967459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2007.08.009 |
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