Generation of Lytic Natural Killer 1.1(+), Ly-49(−) Cells from Multipotential Murine Bone Marrow Progenitors in a Stroma-free Culture: Definition of Cytokine Requirements and Developmental Intermediates

We have developed a stroma-free culture system in which mouse marrow or thymus cells, known to be enriched for lymphoid progenitors, can be driven to generate natural killer (NK) cells. Culture of lineage marker (Lin)(−), c-kit(+), Sca2(+), interleukin (IL)-2/15Rβ (CD122)(−) marrow cells in IL-6, IL...

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Hlavní autoři: Williams, Noelle Sevilir, Moore, Thomas A., Schatzle, John D., Puzanov, Igor J., Sivakumar, P.V., Zlotnik, Albert, Bennett, Michael, Kumar, Vinay
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1997
Témata:
Brief Definitive Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2199105/
https://ncbi.nlm.nih.gov/pubmed/9348320
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