Telomere Length, Telomerase Activity, and Replicative Potential in HIV Infection: Analysis of CD4(+) and CD8(+)T Cells from HIV-discordant Monozygotic Twins

To address the possible role of replicative senescence in human immunodeficiency virus (HIV) infection, telomere length, telomerase activity, and in vitro replicative capacity were assessed in peripheral blood T cells from HIV(+) and HIV(−) donors. Genetic and age-specific effects on these parameter...

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Main Authors: Palmer, Larry D., Weng, Nan-ping, Levine, Bruce L., June, Carl H., Lane, H. Clifford, Hodes, Richard J.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 1997
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2196247/
https://ncbi.nlm.nih.gov/pubmed/9104824
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