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Characterization of a novel bifunctional mutant of staphylokinase with platelet-targeted thrombolysis and antiplatelet aggregation activities

BACKGROUND: Although staphylokianse (SAK) is among the most promising blood dissolving agents, it is far from ideal. It is interesting to hypothesize that the clot lysis efficacy of SAK can be enhanced with direct active platelet binding ability, and at the same time the rethrombosis complication af...

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Autores principales: Chen, Hongshan, Mo, Wei, Su, Huabo, Zhang, Yanling, Song, Houyan
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194782/
https://ncbi.nlm.nih.gov/pubmed/17919340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-88
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