Characterization of a novel bifunctional mutant of staphylokinase with platelet-targeted thrombolysis and antiplatelet aggregation activities

BACKGROUND: Although staphylokianse (SAK) is among the most promising blood dissolving agents, it is far from ideal. It is interesting to hypothesize that the clot lysis efficacy of SAK can be enhanced with direct active platelet binding ability, and at the same time the rethrombosis complication af...

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Bibliografiske detaljer
Main Authors: Chen, Hongshan, Mo, Wei, Su, Huabo, Zhang, Yanling, Song, Houyan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2194782/
https://ncbi.nlm.nih.gov/pubmed/17919340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-88
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