Perinatal Blockade of B7-1 and B7-2 Inhibits Clonal Deletion of Highly Pathogenic Autoreactive T Cells

A number of in vitro studies have suggested that costimulatory molecules B7-1 and B7-2 and their receptor CD28 can promote clonal deletion, and limited in vivo studies have indicated that CD28 is involved in the clonal deletion of some T cells. However, the significance of B7-mediated clonal deletio...

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Bibliographic Details
Main Authors: Gao, Jian-Xin, Zhang, Huiming, Bai, Xue-Feng, Wen, Jing, Zheng, Xincheng, Liu, Jinqing, Zheng, Pan, Liu, Yang
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2002
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193695/
https://ncbi.nlm.nih.gov/pubmed/11956287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20011948
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