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An unstable beta 2-microglobulin: major histocompatibility complex class I heavy chain intermediate dissociates from calnexin and then is stabilized by binding peptide

Proper assembly of the class I heavy chain (HC), beta 2-microglobulin (beta 2m), and peptide must occur in the endoplasmic reticulum (ER) in order for MHC class I molecules to be expressed on the cell surface. Newly synthesized class I HC bind calnexin, an ER resident chaperone. These calnexin-assoc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Rockefeller University Press 1994
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2191763/
https://ncbi.nlm.nih.gov/pubmed/7964491
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