Selective melanocortin MC(4) receptor agonists reverse haemorrhagic shock and prevent multiple organ damage

BACKGROUND AND PURPOSE: In circulatory shock, melanocortins have life-saving effects likely to be mediated by MC(4) receptors. To gain direct insight into the role of melanocortin MC(4) receptors in haemorrhagic shock, we investigated the effects of two novel selective MC(4) receptor agonists. EXPER...

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Detalhes bibliográficos
Main Authors: Giuliani, D, Mioni, C, Bazzani, C, Zaffe, D, Botticelli, A R, Capolongo, S, Sabba, A, Galantucci, M, Iannone, A, Grieco, P, Novellino, E, Colombo, G, Tomasi, A, Catania, A, Guarini, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189765/
https://ncbi.nlm.nih.gov/pubmed/17245369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707115
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