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Induction of rheumatoid antibodies in the mouse. Regulated production of autoantibody in the secondary humoral response

A/J mice were found to produce autoreactive IgM anti-IgG1 in response to secondary immunization with a number of protein antigens. No anti- IgG1 was produced after a single such immunization, indicating that antigen: IgG1 antibody complexes were responsible for inducing the autoreactive response. Th...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1983
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2187336/
https://ncbi.nlm.nih.gov/pubmed/6350525
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