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Enhancement of t lymphocyte functions by Fc fragments of immunoglobulins. I. Augmentation of allogeneic mixed lymphocyte culture reactions requires I-A- or I-B-subregion differences between effector and stimulator cell populations

Fc fragments derived from human Ig were found to be capable of enhancing T cell-mediated, antigen-induced proliferative and mixed lymphocyte culture responses. Maximum enhancement occurred when suboptimal amounts of antigen or suboptimal numbers of stimulator cells were employed. Augmentation of the...

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Bibliografiske detaljer
Main Authors: Morgan, EL, Thoman, ML, Weigle, WO
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1981
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2186150/
https://ncbi.nlm.nih.gov/pubmed/6454744
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