The novel 5-HT1A receptor antagonist, SDZ 216-525, decreases 5-HT release in rat hippocampus in vivo.

1. Recent evidence suggests that the novel compound SDZ 216-525 is a selective and possibly silent 5-HT1A receptor antagonist. Here we have examined the action of SDZ 216-525 on central 5-HT1A autoreceptor function. The experiments involved measurement of drug effects on extracellular 5-HT in the ve...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Sharp, T., McQuade, R., Fozard, J. R., Hoyer, D.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175615/
https://ncbi.nlm.nih.gov/pubmed/8102935
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