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TGFβ(3) signaling activates transcription of the LEF1 gene to induce epithelial mesenchymal transformation during mouse palate development

Epithelial mesenchymal transformation (EMT) of the medial edge epithelial (MEE) seam creates palatal confluence. This work aims to elucidate the molecular mechanisms by which TGFβ(3) brings about palatal seam EMT. We collected mRNA for PCR analysis from individual transforming MEE cells by laser mic...

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Bibliographic Details
Main Authors: Nawshad, Ali, Hay, Elizabeth D.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173726/
https://ncbi.nlm.nih.gov/pubmed/14691138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200306024
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