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An HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transport

We have identified a new pathway of ER-associated degradation in Saccharomyces cerevisiae that functions separately from the HRD/DER pathway comprised of Hrd1p, Hrd3p, Der1p, and Ubc7p. This pathway, termed Hrd1p independent-proteolysis (HIP), is capable of recognizing and degrading both lumenal (CP...

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Hlavní autoři: Haynes, Cole M., Caldwell, Sabrina, Cooper, Antony A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173032/
https://ncbi.nlm.nih.gov/pubmed/12105183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200201053
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