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The cytoplasmic filaments of the nuclear pore complex are dispensable for selective nuclear protein import

The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells. Eight filaments project from the NPC into the cytoplasm and are proposed to function in nuclear import. We investigated the localization and function of two nucleoporin...

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Bibliographic Details
Main Authors: Walther, Tobias C., Pickersgill, Helen S., Cordes, Volker C., Goldberg, Martin W., Allen, Terry D., Mattaj, Iain W., Fornerod, Maarten
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173022/
https://ncbi.nlm.nih.gov/pubmed/12105182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200202088
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