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The ubiquitin proteasome system in synaptic and axonal degeneration: a new twist to an old cycle

The ubiquitin proteasome system (UPS) contributes to the pathophysiology of neurodegenerative diseases, and it is also a major determinant of synaptic protein degradation and activity. Recent studies in rodents and in the fruit fly Drosophila have shown that the activity of the UPS is involved in ax...

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Detalhes bibliográficos
Main Authors: Korhonen, Laura, Lindholm, Dan
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172081/
https://ncbi.nlm.nih.gov/pubmed/15067020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200311091
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