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H-Ras Activation Promotes Cytoplasmic Accumulation and Phosphoinositide 3-Oh Kinase Association of β-Catenin in Epidermal Keratinocytes

The mechanisms underlying downregulation of the cadherin/catenin complexes and β-catenin signaling during tumor progression are not fully understood. We have analyzed the effect of oncogenic H-Ras on E-cadherin/catenin complex formation/stabilization and β-catenin distribution in epidermal keratinoc...

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Autors principals: Espada, Jesús, Pérez-Moreno, Mirna, Braga, Vania M.M., Rodriguez-Viciana, Pablo, Cano, Amparo
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169475/
https://ncbi.nlm.nih.gov/pubmed/10477752
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