Pharmacodynamic Assessment Based on Mutant Prevention Concentrations of Fluoroquinolones To Prevent the Emergence of Resistant Mutants of Streptococcus pneumoniae

The objective of this study was to investigate the relationship between pharmacokinetic and pharmacodynamic parameters, on the basis of the mutant prevention concentration (MPC) concept, and the emergence of resistant mutants of Streptococcus pneumoniae to fluoroquinolone antibacterials. Some clinic...

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Bibliografiska uppgifter
Huvudupphovsmän: Homma, Tomoyuki, Hori, Toshihiko, Sugimori, Giichi, Yamano, Yoshinori
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2007
Ämnen:
Experimental Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151425/
https://ncbi.nlm.nih.gov/pubmed/17664314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01372-06
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