Initial high anti-emetic efficacy of granisetron with dexamethasone is not maintained over repeated cycles.

Eitemau Tebyg

• A randomized, double-blind comparison of granisetron alone and combined with dexamethasone for post–laparoscopic cholecystectomy emetic symptoms()
  gan: Fujii, Yoshitaka, et al.
  Cyhoeddwyd: (2003)
• Granisetron compared with prednisolone plus metopimazine as anti-emetic prophylaxis during multiple cycles of moderately emetogenic chemotherapy
  gan: Sigsgaard, T, et al.
  Cyhoeddwyd: (1999)
• The incidence of anticipatory nausea and vomiting after repeat cycle chemotherapy: the effect of granisetron.
  gan: Aapro, M. S., et al.
  Cyhoeddwyd: (1994)
• Comparison of granisetron alone and granisetron plus dexamethasone in the prophylaxis of cytotoxic-induced emesis.
  gan: Carmichael, J., et al.
  Cyhoeddwyd: (1994)
• Effective cross-over to granisetron after failure to ondansetron, a randomized double blind study in patients failing ondansetron plus dexamethasone during the first 24 hours following highly emetogenic chemotherapy
  gan: de Wit, R, et al.
  Cyhoeddwyd: (2001)