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The structure of a glycogen phosphorylase glucopyranose spirohydantoin complex at 1.8 A resolution and 100 K: the role of the water structure and its contribution to binding.

A glucopyranose spirohydantoin (a pyranose analogue of the potent herbicide, hydantocidin) has been identified as the highest affinity glucose analogue inhibitor of glycogen phosphorylase b (GPb). In order to elucidate the structural features that contribute to the binding, the structures of GPb in...

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Autori principali: Gregoriou, M., Noble, M. E., Watson, K. A., Garman, E. F., Krulle, T. M., de la Fuente, C., Fleet, G. W., Oikonomakos, N. G., Johnson, L. N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2143971/
https://ncbi.nlm.nih.gov/pubmed/9568898
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