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Androgen Ablation Leads to an Upregulation and Intranuclear Accumulation of Deoxyribonuclease I in Rat Prostate Epithelial Cells Paralleling Their Apoptotic Elimination

After androgen ablation by castration, the epithelial cells of the rat ventral prostate are eliminated by apoptosis. The number of cells showing apoptotic chromatin degradation increases with time up to day 3 after castration as verified by in situ end labeling of fragmented DNA. Apoptotic chromatin...

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Autori principali: Rauch, Frank, Polzar, Bernhard, Stephan, Harald, Zanotti, Silvia, Paddenberg, Renate, Mannherz, Hans Georg
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2139838/
https://ncbi.nlm.nih.gov/pubmed/9151693
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