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Calcineurin functions in Ca(2+)-activated cell death in mammalian cells

Calcineurin is a calcium-dependent protein phosphatase that functions in T cell activation. We present evidence that calcineurin functions more generally in calcium-triggered apoptosis in mammalian cells deprived of growth factors. Specifically, expression of epitope-tagged calcineurin A induces rap...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1995
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2120616/
https://ncbi.nlm.nih.gov/pubmed/7593193
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