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Calcineurin functions in Ca(2+)-activated cell death in mammalian cells
Calcineurin is a calcium-dependent protein phosphatase that functions in T cell activation. We present evidence that calcineurin functions more generally in calcium-triggered apoptosis in mammalian cells deprived of growth factors. Specifically, expression of epitope-tagged calcineurin A induces rap...
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Format: | Artigo |
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Language: | Inglês |
Published: |
The Rockefeller University Press
1995
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Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2120616/ https://ncbi.nlm.nih.gov/pubmed/7593193 |
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