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Pseudo-high affinity interleukin 2 (IL-2) receptor lacks the third component that is essential for functional IL-2 binding and signaling

Functional studies of the interleukin 2 receptor (IL-2R) of two (ED515- D and Kit225) IL-2-dependent and three (ED515-I, 3T3-alpha beta 11, and Hut102) IL-2-independent cell lines were done. All of these cell lines appeared to express high as well as low affinity IL-2R. However, ED515- I and 3T3-alp...

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Bibliographic Details
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2119428/
https://ncbi.nlm.nih.gov/pubmed/1402672
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