A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression

Toll-like receptors (TLRs) function as primary sensors that elicit coordinated innate immune defenses through recognition of microbial products and induction of immune and proinflammatory genes. Here we report the identification and biological characterization of a lipopolysaccharide (LPS)-like mole...

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Detalhes bibliográficos
Main Authors: Macagno, Annalisa, Molteni, Monica, Rinaldi, Andrea, Bertoni, Francesco, Lanzavecchia, Antonio, Rossetti, Carlo, Sallusto, Federica
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118317/
https://ncbi.nlm.nih.gov/pubmed/16717116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20060136
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