Ventilation heterogeneity is a major determinant of airway hyperresponsiveness in asthma, independent of airway inflammation

BACKGROUND: Airway hyperresponsiveness is the ability of airways to narrow excessively in response to inhaled stimuli and is a key feature of asthma. Airway inflammation and ventilation heterogeneity have been separately shown to be associated with airway hyperresponsiveness. A study was undertaken...

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Bibliographic Details
Main Authors: Downie, Sue R, Salome, Cheryl M, Verbanck, Sylvia, Thompson, Bruce, Berend, Norbert, King, Gregory G
Format: Artigo
Language:Inglês
Published: BMJ Group 2007
Subjects:
Asthma
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2117268/
https://ncbi.nlm.nih.gov/pubmed/17311839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thx.2006.069682
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