Detection of Chromosomal Structural Alterations in Single Cells by SNP Arrays: A Systematic Survey of Amplification Bias and Optimized Workflow

BACKGROUND: In single-cell human genome analysis using whole-genome amplified product, a strong amplification bias involving allele dropout and preferential amplification hampers the quality of results. Using an oligonucleotide single nucleotide polymorphism (SNP) array, we systematically examined t...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Iwamoto, Kazuya, Bundo, Miki, Ueda, Junko, Nakano, Yoko, Ukai, Wataru, Hashimoto, Eri, Saito, Toshikazu, Kato, Tadafumi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2007
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111048/
https://ncbi.nlm.nih.gov/pubmed/18074030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001306
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla