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Persistent expression of stabilized β-catenin delays maturation of radial glial cells into intermediate progenitors

Transgenic mice expressing stabilized β-catenin in neural progenitors develop enlarged brains resulting from increased progenitor expansion. To more precisely define β-catenin regulation of progenitor fate, we employed a conditional transgenic approach to delete the β-catenin regulatory domain from...

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Sonraí Bibleagrafaíochta
Main Authors: Wrobel, Carolyn N., Mutch, Christopher A., Swaminathan, Sruthi, Taketo, Makoto M., Chenn, Anjen
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2083700/
https://ncbi.nlm.nih.gov/pubmed/17706960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.07.013
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