Paradoxical response of VEGF expression to hypoxia in CSF of patients with ALS

Vascular endothelial growth factor (VEGF) is implicated in motor neurone degeneration. In normal individuals, hypoxia is known to induce an overexpression of VEGF, as measured in CSF. We show that patients with ALS do not manifest this VEGF overexpression in the presence of hypoxia. Although VEGF ge...

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Detalhes bibliográficos
Main Authors: Moreau, C, Devos, D, Brunaud‐Danel, V, Defebvre, L, Perez, T, Destée, A, Tonnel, A B, Lassalle, Ph, Just, N
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2006
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077591/
https://ncbi.nlm.nih.gov/pubmed/16421133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2005.070904
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