Renal defects associated with improper polarization of the CRB and DLG polarity complexes in MALS-3 knockout mice

Kidney development and physiology require polarization of epithelia that line renal tubules. Genetic studies show that polarization of invertebrate epithelia requires the crumbs, partition-defective-3, and discs large complexes. These evolutionarily conserved protein complexes occur in mammalian kid...

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Autores principales: Olsen, Olav, Funke, Lars, Long, Jia-fu, Fukata, Masaki, Kazuta, Toshinari, Trinidad, Jonathan C., Moore, Kimberly A., Misawa, Hidemi, Welling, Paul A., Burlingame, Alma L., Zhang, Mingjie, Bredt, David S.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064744/
https://ncbi.nlm.nih.gov/pubmed/17923534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200702054
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