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Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2–7 loading

The origin recognition complex (ORC) nucleates DNA replication initiation in eukaryotic cells. This six-protein complex binds replication origin DNA, recruits other initiation factors, and facilitates loading of the DNA helicase. Studying the function of individual ORC subunits during pre-RC formati...

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Bibliografiske detaljer
Main Authors: Chen, Shuyan, de Vries, Milan A., Bell, Stephen P.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049192/
https://ncbi.nlm.nih.gov/pubmed/18006685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1596807
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