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The EWS–Oct-4 fusion gene encodes a transforming gene

The t(6;22)(p21;q12) translocation associated with human bone and soft-tissue tumours results in a chimaeric molecule fusing the NTD (N-terminal domain) of the EWS (Ewing's sarcoma) gene to the CTD (C-terminal domain) of the Oct-4 (octamer-4) embryonic gene. Since the N-terminal domains of EWS...

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Bibliografiske detaljer
Main Authors: Lee, Jungwoon, Kim, Ja Young, Kang, In Young, Kim, Hye Kyoung, Han, Yong-Mahn, Kim, Jungho
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2049031/
https://ncbi.nlm.nih.gov/pubmed/17564582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070243
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