Bioavailability of the antiemetic metopimazine given as a microenema

The absorption of the antiemetic metopimazine (MPZ) given as a single dose of (a) 40 mg microenema, (b) 40 mg orally and (c) 10 mg as a 60 min i.v. continuous infusion was investigated in six healthy volunteers. Blood samples were drawn and the serum concentrations of MPZ and its acid metabolite wer...

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Bibliographic Details
Main Authors: HERRSTEDT, JØRN, JØRGENSEN, MORTEN, ANGELO, HELLE RIIS, RASSING, MARGRETHE RØMER, MØLLER-SONNERGAARD, JØRN, DOMBERNOWSKY, PER
Format: Artigo
Language:Inglês
Published: 1996
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042615/
https://ncbi.nlm.nih.gov/pubmed/8799530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.35220.x
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