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Effects of a single oral dose of sparfloxacin on ventricular repolarization in healthy volunteers

1Sparfloxacin, a new fluoroquinolone, slightly increases the duration of the QT interval. Reverse rate-dependence of QT interval prolongation has been shown for many agents that are known to prolong QT interval duration, and QT prolongation at slow heart rates may be a risk factor for torsades de po...

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Main Authors: DEMOLIS, J.-L., CHARRANSOL, A., FUNCK-BRENTANO, C., JAILLON, P.
格式: Artigo
語言:Inglês
出版: 1996
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2042611/
https://ncbi.nlm.nih.gov/pubmed/8799513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1996.03394.x
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