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Altered ATP7A expression and other compensatory responses in a murine model of Menkes disease

Mutations in the copper-transporter ATP7A lead to severe neurodegeneration in the mottled brindled hemizygous male (Mo(Br/y)) mouse and human patients with Menkes disease. Our earlier studies demonstrated cell-type and stage-specific changes in ATP7A protein expression during postnatal neurodevelopm...

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Autores principales: Niciu, Mark J., Ma, Xin-Ming, Meskini, Rajaâ El, Pachter, Joel S., Mains, Richard E., Eipper, Betty A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2040029/
https://ncbi.nlm.nih.gov/pubmed/17588765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.05.004
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