CS-886, a new angiotensin II type 1 receptor antagonist, ameliorates glomerular anionic site loss and prevents progression of diabetic nephropathy in Otsuka Long-Evans Tokushima fatty rats.

BACKGROUND: Diabetic nephropathy is a leading cause of end-stage renal disease in industrialized countries. Previous studies have documented that angiotensin converting enzyme (ACE) inhibitors consistently reduce albuminuria and retard the progression of diabetic nephropathy. However, the involvemen...

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Main Authors: Koga, Kohachiro, Yamagishi, Sho-ichi, Takeuchi, Masayoshi, Inagaki, Yosuke, Amano, Shinjiro, Okamoto, Tamami, Saga, Tsuyoshi, Makita, Zenji, Yoshizuka, Mitsuaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039939/
https://ncbi.nlm.nih.gov/pubmed/12477969
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