Signaling through CD43 regulates CD4 T-cell trafficking

The mucin-like protein CD43 is excluded from the immune synapse, and regulates T-cell proliferation as well as T-cell migration. While the CD43 cytoplasmic domain is necessary for regulation of T-cell activation and proliferation, the mechanism via which CD43 regulates trafficking is not well define...

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Autores principales: Mody, Purvi D., Cannon, Judy L., Bandukwala, Hozefa S., Blaine, Kelly M., Schilling, Alexander B., Swier, Kevin, Sperling, Anne I.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2007
Materias:
Immunobiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2018673/
https://ncbi.nlm.nih.gov/pubmed/17638845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-01-065276
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