Identification of an antagonist that selectively blocks the activity of prostamides (prostaglandin-ethanolamides) in the feline iris

BACKGROUND AND PURPOSE: The prostamides (prostaglandin-ethanolamides) and prostaglandin (PG) glyceryl esters are biosynthesized by COX-2 from the respective endocannabinoids anandamide and 2-arachidonyl glycerol. Agonist studies suggest that their pharmacologies are unique and unrelated to prostanoi...

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Detalhes bibliográficos
Main Authors: Woodward, D F, Krauss, A H, Wang, J W, Protzman, C E, Nieves, A L, Liang, Y, Donde, Y, Burk, R M, Landsverk, K, Struble, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013905/
https://ncbi.nlm.nih.gov/pubmed/17179945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706989
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