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Φ-Value analysis of a three-state protein folding pathway by NMR relaxation dispersion spectroscopy

Experimental studies of protein folding frequently are consistent with two-state folding kinetics. However, recent NMR relaxation dispersion studies of several fast-folding mutants of the Fyn Src homology 3 (SH3) domain have established that folding proceeds through a low-populated on-pathway interm...

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Autori principali: Neudecker, Philipp, Zarrine-Afsar, Arash, Davidson, Alan R., Kay, Lewis E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2000424/
https://ncbi.nlm.nih.gov/pubmed/17898173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705097104
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