DIMINISHED DEGRADATION OF MYELIN BASIC PROTEIN BY ANTI-SULFATIDE ANTIBODY AND INTERFERON-γ IN MYELIN FROM GLIA MATURATION FACTOR-DEFICIENT MICE

In this study we show the effect of anti-sulfatide (RmAb) antibodies and inflammatory cytokines, TNF-α and IFN-γ in inducing myelin basic protein (MBP) degradation in myelin isolated from control wild type (WT) and glia maturation factor (GMF)-deficient (GMF-KO) mice. GMF was not detected in isolate...

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Autors principals: Menon, Krishnakumar, Wu, Yanghong, Haas, Joel, Sahu, Shailendra K., Yang, Baoli, Zaheer, Asgar
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1992520/
https://ncbi.nlm.nih.gov/pubmed/17383764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neures.2007.02.010
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