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Affinity and efficacy of racemic, (+)-, and (-)-methacholine in muscarinic inhibition of [3H]-noradrenaline release.

The right postganglionic sympathetic nerves of rat isolated perfused hearts (previously loaded with [3H]-noradrenaline) were stimulated electrically with 10 trains of 10 pulses at 10 Hz. The inhibition by methacholine of stimulation-evoked [3H]-noradrenaline overflow into the perfusate (determined i...

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Detalhes bibliográficos
Main Authors: Fuder, H., Jung, B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1987304/
https://ncbi.nlm.nih.gov/pubmed/3884076
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