Genome bioinformatic analysis of nonsynonymous SNPs

BACKGROUND: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the most common of which is the non-synonymous single nucleotide polymorphism (nsSNP). It would be an advantage if the functiona...

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Autors principals: Burke, David F, Worth, Catherine L, Priego, Eva-Maria, Cheng, Tammy, Smink, Luc J, Todd, John A, Blundell, Tom L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
Matèries:
Methodology Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978506/
https://ncbi.nlm.nih.gov/pubmed/17708757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-301
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