Treatment of malignant hypercalcaemia with clodronate.

We have assessed the effects of clodronate (dichloromethylene diphosphonate; Cl2MDP 0.8-3.2g daily by mouth for up to 3 months) in 17 episodes of hypercalcaemia and osteolysis due to carcinoma. Clodronate reduced serum calcium in 14 episodes and bone resorption in all patients. These remained suppre...

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Autores principales: Percival, R. C., Paterson, A. D., Yates, A. J., Beard, D. J., Douglas, D. L., Neal, F. E., Russell, R. G., Kanis, J. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1985
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1977044/
https://ncbi.nlm.nih.gov/pubmed/3158326
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